Description:  Progressive retinal atrophy is an inherited disease that occurs in many dog breeds and manifests itself in various forms. The form of a progressive rod and cone degeneration is photoreceptor degeneration and occurs at different dog ages. The genetic disorder causes the degeneration of retinal cells in the eye. The rods are first affected; therefore, night blindness occurs first. Consequently, the cones are impairment, resulting in the complete blindness of the animals in optimal lighting conditions, such as daylight. However, the time of onset may vary and depends on the breed of the dog from 2 to 12 years.

Inheritance: autosomal recessive

Mutation: c.5G>A in PRCD gene (previous designation 1298G>A)

Sample: EDTA whole blood (1.0 ml) or 2 buccal brushes. For official purposes, the confirmation of the dog’s identity by Veterinarian is recommended.

The analysis is suitable for the following breeds: American Eskimo Dog, Australian Cattle Dog, Australian Shepherd, Australian Shepherd (Miniature Australian Shepherd), Australian Stumpy Tail Cattle Dog, Basenji, Chesapeake Bay Retriever, Chinese Crested Dog, Cockapoo, Cocker Spaniel (American, England), English Cocker Spaniel, Entlebucher Mountain Dog, German shepherd, Lapphund (Finnish, Swedish), Goldendoodle, Golden Retriever, Karelian Bear Dog, Kuvasz, Labradoodle, Labrador Retriever, Lapponian Herder, Magyar Vizsla, Norwegian Elkhound, Papillon, Poodle (Dwarf, Miniature, Toy), Terrier (Silky, Yorkshire), Water Dog (Portuguese, Spanish)

Notes: PRA-prcd can also occur in other breeds not listed